B N Reddy
Osmania University, India
Title: Disease outbreaks due to mycotoxin poisoning in developing countries: risks and challenges of food safety management
Biography
Biography: B N Reddy
Abstract
Aflatoxicoses are diseases caused by aflatoxins in livestock, domestic animals and humans throughout the world. Exposure tornthese mycotoxins is mostly by ingestion but also occurs by the dermal and inhalation routes. The susceptibility of individuals tornmycotoxins varies considerably depending on species, age, sex and nutrition. Acute mycotoxicoses can cause serious and sometimesrnfatal diseases also. The possibility of mycotoxin intoxication should be considered when a sudden acute disease occurs in a largernpopulation when there is no evidence of infection with a known etiological agent and there is no improvement in the clinical picturernfollowing treatment. The global nature of the mycotoxin problem is based on well-documented human mycotoxicoses such asrnergotism in Europe, alimentary toxic aleukia in Russia, acute aflatoxicoses in South and East Asia and human primary liver cancerrnin Africa and South East Asia. Ochratoxin A is suspected to play a role in Balkan endemic nephropathy in Yugoslavia and chronicrninterstitial nephritis in North Africa. The present paper reviews the disease outbreaks of aflatoxicoses in developing countries with anrnemphasis on Indian cases, due to the ingestion of contaminated food and feed with aflatoxins